2.5: Tissue Mechanics Across Time and Length Scales

Organizers:

  • Ottman Tertuliano, University of Pennsylvania
  • Claire Acevedo, University of California San Diego
  • David Kammer, ETH Zurich

Description:

Tissues are inherently hierarchical, living structures. Their constituents assemble purposefully starting from the nanoscale to design macroscopically functional organs while simultaneously imbuing the tissues with classically disparate mechanical properties. The hierarchical organization of constituents in tissues is dynamic by nature; it changes via cell-mediated remodeling with aging, disease, and mechanical stimulation. The goal of this symposium is to bring together researchers with expertise in theoretical, computational, and experimental approaches to quantitatively investigate how hierarchical structure fundamentally couples to mechanical properties in tissue and how this coupling dictates tissue health and function across length and time scales.


Topics of interest:

This symposium solicits contributions in all fields related to mechanics of tissues across length and time scales with topics including but not limited to:

  • fracture, damage or rupture nucleation/initiation in tissues
  • bridging time or length scales in tissue mechanical properties
  • mechanisms of tissue repair and regeneration, aging, and morphogenesis
  • cellular and function impairment in healthy versus diseased tissues
  • how cells affect tissue properties over length and time scales
  • mechanics of musculoskeletal tissues, bone, tendon, muscles, joint, spine, etc.

Contributions to novel modeling approaches and experimental techniques (including imaging) are particularly welcome.