Lindesmith, L., McDaniel, J., Changela, A., Verardi, R., Kerr, S., Costantini, V., Brewer-Jensen, P. , Mallory, M., Voss, W., Boutz, D., Blazeck, J., Ippolito, G., Vinje, J., Kwong, P., Georgiou, G., and Baric, R. (2019) “Sera antibody repertoire analyses reveal mechanisms of broad and pandemic strain neutralizing responses after human norovirus vaccination.” Immunity. 50(6):1530-1541.
Triplett, T*., Garrison, K*., Marshall, N*., Donkor, M*., Blazeck, J., Lamb, C., Qerqez, A., Tano, Y., Lu, W.-C., Karamitros, C., Ford, K., Tan, B., Zhang, M., Kumada, Y., Yemeny, M.S., Sentandreu, E., Fromm, G., Tiziani, S., Schreiber, T. H., Manfredi, M., Ehrlich, L. I. R., Stone, E., and Georgiou, G. (2018) “Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.” Nature Biotechnology, 36:758–764.
Blazeck, J., Hill, A., Jamoussi, M., Pan, A., Miller, J., Alper, H. S. (2015) “Metabolic engineering of Yarrowia lipolytica for itaconic acid production.” Metabolic Engineering. 32:66-73.
Liu, L., Markham, K., Blazeck, J., Zhou, N., Leon, D., Otoupal, P., Alper, H. S. (2015) “Surveying the lipogenesis landscape in Yarrowia lipolytica through understanding the function of a Mga2p regulatory protein mutant.” Metabolic Engineering. 31:102-111.
Blazeck, J., Miller, J., Pan, A., Gengler, J., Holden C., Alper, H. S. (2014) “Metabolic Engineering of Saccharomyces cerevisiae for itaconic acid production.” Applied Microbiology and Biotechnology. 98:8155-8164.
Blazeck, J.*, Hill, A.*, Liu, L.*, Knight, R. Miller, J., Pan, A., Otoupal, P., Alper, H. S. (2014) “Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production.” Nature Communications. 5(3131) doi:10.1038/ncomms4131.
Blazeck, J., Liu, L., Knight, R., Alper, H. S. (2013) “Heterologous production of pentane in the oleaginous yeast Yarrowia lipolytica.” Journal of Biotechnology. 165(3-4): 184-194.
Blazeck, J., Reed, B., Garg, R., Gerstner, R., Pan, A., Agarwala, V., Alper, H. S. (2013). “Generalizing a Hybrid Synthetic Promoter Approach in Yarrowia lipolytica.” Applied Microbiology and Biotechnology. 97(7): 3037-3052.
Blazeck, J. and Alper, H. (2013). “Promoter Engineering: Recent Advances in Controlling Transcription at the Most Fundamental Level.” Biotechnology Journal. 8(1): 46-58.
Blazeck, J., Garg, R., Reed, B., Alper, H. S. (2012). “Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters.” Biotechnology and Bioengineering. 109(11) 2884-2995.
Lanza, A., Blazeck, J., Crook, N. Alper, H. S. (2012). “Linking Yeast Gcn5p Catalytic Function and Gene Regulation Using a Quantitative, Graded Dominant Mutant Approach.” PLoS ONE. 7(4): e36193.
Reed, B., Blazeck, J., Alper, H. S. (2012). “Evolution of an alkane-inducible biosensor for increased responsiveness to short-chain alkanes.” Journal of Biotechnology. 158(3): 75-79.
Blazeck, J.*, Liu, L.*, Redden, H., Alper, H. S. (2011). “Tuning Gene Expression in Yarrowia lipolytica by a Hybrid Promoter Approach.” Applied and Environmental Microbiology. 77(22): 7905-7914.
Blazeck, J. and Alper, H. (2010). “Uncovering latent xylose utilization potential in Saccharomyces cerevisiae.” Biofuels. 1(5): 681-684.
Blazeck, J. and Alper, H. (2010). “Systems metabolic engineering: Genome-scale models and beyond.” Biotechnology Journal. 5(7): 647-649.
Patents
Administration of kynurenine depleting enzymes for tumor therapy.
U.S. Patent No. 9,808,486 B2
George Georgiou, Everett Stone, Nicholas Marshall, John Blazeck, Wei-cheng Lu.
Composition and methods for fungal lipid production.
U.S. Patent No. 9,896,691.
Hal Alper, John Blazeck, Leqian Liu, Andrew Hill.