Pathology Dynamics

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Conference Abstracts

Click on the abstract to be taken to the paper.

Mehra, N., A. Sedler, C.S. Mitchell.  (2018). Informatics-based Literature Mapping to Expedite Research for Chronic Myeloid Leukemia.  Biomedical Engineering Society, Atlanta, GA.

Wright, E., K. Jordan, C.S. Mitchell.  (2018). Effects of BACE Inhibitors on Alzheimer’s Disease Cognition.  Biomedical Engineering Society, Atlanta, GA.

Sedler, A., C.S. Mitchell.  (2018).  Systematic Analysis of the Topic Landscape of Aging and Alzheimer’s Disease Literature.  Biomedical Engineering Society, Atlanta, GA.

Murphy, J., K. Jordan, A. Sedler, K. Denson, C.S. Mitchell.  (2018). Biocuration: Improving Automation, Productivity, Accuracy and Quality Control.  Biomedical Engineering Society, Atlanta, GA.

Khamankar, N., L. Bond, P. Ganguly, N. Mallet, C.S. Mitchell (2018).  Optimizing Bi-PAP Intervention for ALS using Predictive Medicine. Biomedical Engineering Society, Atlanta, GA.

Bond, L., P. Ganguly, N. Khamankar, N. Mallet, C.S. Mitchell.  (2018).  Optimizing PEG “Feeding Tube” Intervention for ALS using Predictive Medicine.  Biomedical Engineering Society, Atlanta, GA.

Lee, A.S., S. Travaglino, C.S. Mitchell.  (2018). Dynamic Meta-Analysis Approach to In Silico Models of Temporal Multiscalar Neurophysiology. Biomedical Engineering Society, Atlanta, GA.

Khamankar, N., L. Bond, P. Ganguly, N. Mallet, C.S. Mitchell.  (2018). Optimizing Bi-level Positive Airway Pressure Protocols for Patients with Amyotrophic Lateral Sclerosis.  American Neurology Association, Atlanta, GA.

Sedler, A., C.S. Mitchell. Analysis of the Topic Landscape of Aging and Alzheimer.  (2018). American Neurology Association, Atlanta, GA.

Bond, L., P. Ganguly, N. Khamankar, N. Mallet, C.S. Mitchell.  (2018). Analysis of Percutaneous Endoscopic Gastrostomy Usage in Treatment of Amyotrophic Lateral Sclerosis Patients.  American Neurology Association, Atlanta, GA.

Lee, A, S. Travaglino, T. Kittel, and C.S. Mitchell.  (2017). Towards syncing polytherapy to the multi-factorial dynamics of the SOD1 G93A ALS pathology.  Society for Neuroscience, Washington DC.

Kittel, T., A. Lee, T. Bach, C.S. Mitchell.  (2017). Data enabled design of multi-factorial disease treatment paradigms: a case study of Amyotrophic Lateral Sclerosis.  National Academy of Engineers.  Atlanta, GA.

Mitchell, C.S. and G. Coan.  (2016). Pathophysiology Informatics: Integrating Multi-scalar Experimental Data to Predict Pathology. Biomedical Engineering Society, Minneapolis, MN.

Kittel, T., R. Kim, T. Zhang, G. Coan. C.S. Mitchell.  (2016).  Meta-analysis of treatment efficacy in relation to disease progression in the G93A SOD1 mouse model of Amyotrophic Lateral Sclerosis.  Society for Neuroscience, San Diego, CA.(Wednesday P.M.)

Zhang, K., T. Bach, D. Vitharana, G. Coan, C.S. Mitchell.  (2016).  A dynamic meta-analysis of apoptosis, bioenergetics, and oxidative stress molecular mechanisms in the G93A SOD1 transgenic ALS mouse.  Society for Neuroscience, San Diego, CA.(Sunday A.M.)

Huber, C., T. May, G. Coan, C.S. Mitchell.  (2016).  A meta-analysis assessing the influence of tau and amyloid-beta on cognitive decline in a preclinical model of Alzheimer’s Disease.  Society for Neuroscience, San Diego, CA.(Sunday A.M.)

Jordan, K., J. Murphy, A. Singh, G. Coan, C.S. Mitchell.  (2016). An examination of noninflammatory astrocyte secretions of glutamate in the SOD1 G93A ALS mouse model.  Society for Neuroscience, San Diego, CA.(Sunday A.M.)

Vernon, I., Y. Shi, M. Jensen, Z. Seiling, C.S. Mitchell.  (2015). A temporal assessment of excitability in the SOD1 G93A Amyotrophic Lateral Sclerosis mouse model.  Society for Neuroscience.  Chicago, IL.

Kim, R., C. Irvin, J. Knipe, C.S. Mitchell (2015).  Leveraging informatics to assess the SOD1 G93A amyotrophic lateral sclerosis mouse model.  Society for Neuroscience.  Chicago, IL.

Mitchell, C.S., S. Hollinger, S. Goswami, M. Polak, R. Lee, J. Glass. (2015).  Elucidating the potential role of antecedent disease in Amyotrophic Lateral Sclerosis.  26th International Symposium on ALS/MND.  Orlando, FL.

Mitchell, C.S. (2014).  Hypervigilant regulation as ALS-cause: evidence from ALS patients and transgenic mouse models.  International Motoneuron Society, Halifax, Nova Scotia.

Lee, R.H. and C.S. Mitchell.  (2014). Role of subthreshold Ca-dependent potassium currents in motoneuron firing properties.  Society for Neuroscience. Washington DC.

Pfohl, S., M Halicek, and C.S. Mitchell (2014).  A meta-analysis of rotarod experimental protocols in the G93A SOD1 transgenic ALS mouse.  Society for Neuroscience. Washington DC.

Coan, G., J.D. Glass, C.S. Mitchell (2014).  Post-mortem assessment of potential ALS biological predictors: An analysis of 51 patient autopsies. Society for Neuroscience. Washington DC.

Ammar, Z, A Foley,C.S. Mitchell, R.H. Lee. (2013).  Analysis of Alzheimer’s Disease transgenic mouse Tg2576 research II: Does Abeta correlate with Morris water maze escape latency? Society for Neuroscience, San Diego, CA.

Foley, A, Z Ammar, C.S Mitchell, R.H. Lee. (2013).  Analysis of Alzheimer’s Disease transgenic mouse Tg2576 research I: Survey of experimental studies.  Society for Neuroscience, San Diego, CA.

Mitchell, C.S., M. Halicek, R. Kim, K. Tilva, R.H. Lee (2013). Analysis of ALS transgenic mouse research II: Preliminary meta-analyses of G93A transgenic mouse experimental studies. Society for Neuroscience, San Diego, CA.

Mitchell, C.S., M. Halicek, R. Kim, K. Tilva, R.H. Lee (2013).  Analysis of ALS transgenic mouse research I:  1,622 papers and counting.  Society for Neuroscience, San Diego, CA.

R.H. Lee and C.S. Mitchell (2012).  Interaction between sodium PICs and motoneuron firing properties. Society for Neuroscience, New Orleans, LA.

Mitchell, C.S., J.D. Glass, R.H. Lee (2012).  Identification of prognostic and therapeutic predictors in Amyotrophic Lateral Sclerosis. Society for Neuroscience, New Orleans, LA.

Croft, E., J. Figanbaum, C.S. Mitchell.  (2012) A quantitative assessment of pathophysiological axonal motor-cargo traffic. Society for Neuroscience, New Orleans, LA.

Tilva, K. and Mitchell, C.S. (2012). Dynamic meta-analysis of the G93A SOD1 mouse model predicts the pathology, progression, and treatment responses of ALS, Society for Neuroscience, New Orleans, LA.

R.H. Lee and C.S. Mitchell (2011). Reconceptualization of the motoneuron current-frequency relationship. Society for Neuroscience conference, Washington DC.

Mitchell, C.S. and R.H. Lee (2011).  Pathological axonal transport I: Protein aggregation, molecular motor deregulation and mutation. Society for Neuroscience conference, Washington DC.

Orticelli, A.M. and C.S. Mitchell (2011). Pathological axonal transport II:  binding cooperativity, ATP, and tau.  Society for Neuroscience conference, Washington DC.

Lee, R.H. and C.S. Mitchell (2010). Role of motoneuron C-terminals in repetitive firing. Society for Neuroscience Conference, San Diego, CA.

Mitchell, C.S. and R.H. Lee (2010).  Dynamic Meta-Analysis of the G93A SOD1 mouse model:  Pathology dynamics and combination treatment predictions.  21st Annual International Symposium on Amyotrophic Lateral Sclerosis and Motor Neuron Disease, Orlando, FL.

Mitchell, C.S. (2010).  ALS Mechanisms, Dynamics, and Treatment: Analytical and Modeling Predictions. International Motoneuron Society Conference, Paris, France.

Mitchell, C.S. and R.H. Lee (2010).  Cargo distributions differentiate motoneuron axonal transport impairment mechanisms in ALS.  Society for Neuroscience Conference, San Diego, CA.

Mitchell, C.S. and R.H. Lee (2009).  Dynamical predictions of a system–spanning model of ALS and its response to hypothetical treatments. Society for Neuroscience conference, Chicago, IL.

Mitchell, C.S., C.M. Simon, M.C. LaPlaca, R.H. Lee (2009).  A Comprehensive Approach to Understanding Spinal Cord Injury. Christopher Reeves Foundation Symposium, Atlanta, GA.

Lee, R.H. and C.S. Mitchell (2009).  Relational Analysis of Motoneuron Firing Properties.  Society for Neuroscience  conference, Chicago, IL.

Mitchell, C.S. and R.H. Lee (2008).  A Re-examination of the AHP:  Is it diffusion limited?  2008 Mechanisms of Plasticity and Disease in Motoneurons,  Seattle, WA.

Mitchell, C.S. and R.H. Lee (2008).   Comprehensive examination of secondary spinal cord injury and potential single and combinatorial neuroprotective therapeutic strategies , 26th Annual National Neurotrauma Symposium, Orlando, FL.

Mitchell C.S. and R.H. Lee (2008).  A Reconceptualization of the relationship between spike afterhypolarization and firing rate in lumbar motoneurons of the adult cat.   Society for Neuroscience, Washington DC.

Mitchell, C.S. and R.H. Lee (2008).  A quantitative assessment of secondary injury dynamics and potential multi-faceted neuroprotective therapeutics.  Society for Neuroscience, Washington DC.

Mitchell, C.S. and R.H. Lee (2007).  Comparison of degenerate NMDA-receptor models in the context of a larger model. Society for Neuroscience, San Diego, CA.

Mitchell, C.S. and R.H. Lee (2007).  A computational model of secondary traumatic injury.  Society for Neuroscience, San Diego, CA.

Mitchell, C.S. and R.H. Lee (2007).  Biological Model Analysis:  What does complexity theory have to offer? Integrative Systems Biology Symposium, Georgia Institute of Technology, Atlanta, GA.

Mitchell CS, Feng S, Lee RH. A model of glutamate spillover on the N-methyl-D-aspartate receptors of the cerebellar glomerulus. Society for Neuroscience; 2006; Atlanta, GA,

Articles

Recent News

  • Dr. Mitchell Recognized as Joint Faculty Outstanding Undergraduate Research Mentor April 30, 2022
  • Lab Alumni Mira Mutnick Awarded Prestigious Goldwater Scholarship April 30, 2022
  • Georgia Tech Names PhD Student Raghav Tandon Online TA of the Year April 30, 2022
  • Undergraduate Kevin McCoy Wins Sigma Xi Best Undergraduate Research Award and Named Outstanding Senior April 20, 2022
  • Pathology Dynamics Lab Gathers to Celebrate October 22, 2021

Archive

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