IRE for brain cancer using canine patients with spontaneous disease:
Canine patient 1 week post IRE
Canine patient 1 month post IRE
Spontaneous canine glioma models are exceptional clinical translation of IRE for brain tumor treatment:
– Canines develop spontaneous gliomas 3X more often than people
– Large animal studies allow for testing of clinical size probes
– Pathophysiology of spontaneous tumors are analogous to brain cancer in people
Preclinical models allow for evaluation of clinical safety and feasibility of irreversible electroporation implementation in the clinic.
