Publications

Click to view Dr. Rudolph Gleason publications on PubMed

Representative Publications

1. Multi-scaled experimental frameworks for vascular biomechanics and growth & remodeling in health and disease.

  1. Kim CW, Pokutta-Paskaleva A, Kumar S, Timmins LH, Morris AD, Kang DW, Dalal S, Chadid T, Kuo K, Raykin J, Li H, Yanagisawa H, Gleason RL, Jo H, Brewster LP. (2017) Disturbed flow promotes arterial stiffening through thrombospondin-1 (TSP-1). (2017) Circulation. ePub ahead of print. PMID: 28778947
  2. Wang R, LP Brewster, RL Gleason (2013) In-situ characterization of the uncrimping process of arterial collagen fibers using two-photon confocal microscopy and digital image correlation. Journal of Biomechanics. 46(15):2726-2729. PMID: 24050510
  3. Wan W, RL Gleason (2012) Dysfunction in elastic fiber formation in fibulin-5 null mice abrogates the evolution in mechanical response of carotid arteries during maturation. American Journal of Physiology: Heart & Circulation Physiolology. 304(5):H674-86. PMID: 23241326.
  4. Zaucha M, R Gauvin, FA Auger, L Germain, RL Gleason (2011) Biaxial biomechanical properties of media and adventitial equivalents and bilayer blood vessel substitutes created by self-assembly. Journal of the Royal Society Interface. 8(55):244-256. PMID: 20554564.

3. Characterizing mechanically mediated acute and long-term adaptations of lymphatic vessels in the development and progression of lymphedema.

  1. Nelson TS, Nepiyushchikh Z, Hooks JST, Razavi MS, Lewis T, Clement CC, Thoresen M, Cribb MT, Ross MK, Gleason RL Jr, Santambrogio L, Peroni JF, Dixon JB (2019) Lymphatic remodelling in response to lymphatic injury in the hind limbs of sheep. Nature Biomedical Engineering. ePub ahead of print. PMID: 31873209.
  2. Razavi M, Nelson T, Nepiyushchikh A, Gleason RL, Dixon JB. (2017) The relationship between lymphangion chain length and maximum pressure generation established through in vivo imaging and computational modeling. American Journal of Physiology: Heart & Circ Physiol. PMID: 28778909
  3. Caulk AW, Dixon JB, Gleason RL (2016) A lumped parameter model of mechanically mediated acute and long-term adaptations of contractility and geometry in lymphatics for characterization of lymphedema. Biomech Model Mechanobiol. 15(6):1601-1618 PMID: 27043026.
  4. Caulk AW, Nepiyushechikh ZV, Shaw R, Dixon JB, Gleason RL (2015) Quanitification of the passive and active biaxial mechanical behavior and microstructural organization of rat thoracic ducts. Journal of the Royal Society Interface. 12(108). pii: 20150280. PMID:26040600.

4. Identify mechanisms of early on-set atherosclerosis with HIV and highly active antiretroviral therapy (HAART) and to identify low-cost diagnostics and effective prevention and treatment strategies for non-AIDS co-morbidities, with emphasis on populations in low-resource settings.

  1. Gleason RL, Caulk AW, Seifu D, Parker I, Vidakovic B, Getenet H, Assefa G, Amogne W (2015) Current efavirenz (EFV) or ritonavir-boosted lopinavir (LPV/r) use correlates with elevated markers of atherosclerosis in HIV-infected subjects in Addis Ababa, Ethiopia. Plos ONE. 10(4):e0117125. PMID: 25915208.
  2. Gleason RL, Caulk AW, Seifu D, Rosebush J, Shapiro AM, Schwartz MH, Ross-Eckard A, Amogne W, and Workeabebe A (2016) Efavirenz and ritonavir-boosted lopinavir use exhibited elevated markers of atherosclerosis across age groups in people living with HIV in Ethiopia. Journal of Biomechanics. 49(13):2584-2592. PMID: 27270208.
  3. Caulk AW, Soler J, Platt MO, Gleason RL (2015) Efavirenz treatment causes arterial stiffening in Apolipoprotein E-null mice. Journal of Biomechanics 48(10):2176-80. PMID: 26050957.
  4. Hansen L, I Parker, RL Sutliff, MO Platt, Gleason RL (2013) Endothelial dysfunction, arterial stiffening, and intima-media thickening in large arteries from HIV-1 transgenic mice. Annals of Biomedical Engineering. 41(4):682-93. PMID: 23180031.

5. Reducing maternal & perinatal mortality through low-cost, early diagnosis of risk in the rural developing world.

  1. Tolentino L, Yigeremu M, Teklu S, Attia S, Weiler M, Frank N, Gleason RL (2019) 3D camera anthropometry to assess risk of cephalopelvic disproportion-related obstructed labor in Ethiopia. Interface Focus. 9(5):20190036.
  2. Gleason RL, Yigeremu M, Debebe T, Teklu S, Zewdeneh D, Weiler M, Frank N, Tolentino L, Attia S, Dixon JB, Kwon C, Pokutta-Paskaleva A, Gleason KA. (2018) A safe, low-cost, easy-to-use 3D camera platform to assess risk of obstructed labor due to cephalopelvic disproportion. Plos ONE. 13(9):e0203865. PMID: 30216374.
  3. Clark GL, Pokutta-Paskaleva AP, Lawrence DJ, Lindsey SH, Desrosiers L, Knoepp LR, Bayer CL, Gleason RL, Miller KS. Smooth muscle regional contribution to vaginal wall function. Interface Focus. 2019 Aug 6;9(4):20190025.