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Center for Integration of the Origins of Life

Center for Integration of the Origins of Life

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Research

  • Insertions in RNA polymerase genes suggest episodes of domain insertion around the time of the last bacterial common ancestor
    by Claudia Alvarez Carreno
    RNA polymerases are multi-subunit proteins that transcribe genes encoded in DNA to messenger RNA (mRNA). The mRNA is then translated into protein at the ribosome. In a recent publication in Protein Science, iCOOL affiliate Claudia Alvarez Carreno, Co-I Anton Petrov, and PI Loren Williams describe,… Read more: Insertions in RNA polymerase genes suggest episodes of domain insertion around the time of the last bacterial common ancestor
  • If biopolymers are required to make other biopolymers, where did the first biopolymers come from?
    by Jessica C Bowman
    October 20, 2024. In life on modern Earth, enzymes made of protein catalyze the formation of most other types of biopolymers. These enzymes have been evolving for billions of years and have become very efficient at assembling nucleic acid, carbohydrate, and lipid biopolymers from their… Read more: If biopolymers are required to make other biopolymers, where did the first biopolymers come from?
  • A new bioinformatics tool: RiboVision2
    by Jessica C Bowman
    Co-I Anton Petrov, PI Loren Williams, and students published RiboVision2, an open-source tool for understanding RNA structure and evolution. RiboVision2 is a web server designed to visualize the phylogenetic, structural, and evolutionary properties of ribosomal RNAs, simultaneously, at the levels of primary, secondary, and three-dimensional… Read more: A new bioinformatics tool: RiboVision2

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