Selected Publications
1) Chiba, S.; Frey, S. J.; Halfmann, P. J.; Kuroda, M.; Maemura, T.; Yang, J.; Wright, E. R.; Kawaoka, Y.; Kane, R. S. “Multivalent Nanoparticle-Based Vaccines Protect Hamsters Against SARS-CoV-2 After a Single Immunization”, Communications Biology, 2021, 4, 597.
2) Halfmann, P.; Castro, A.; Loeffler, K.; Frey, S. J.; Chiba, S.; Kawaoka, Y.; Kane R.S. “Potent Neutralization of SARS-CoV-2 Including Variants of Concern by Vaccines Presenting the Receptor-Binding Domain Multivalently from Nanoscaffolds.” Bioengineering & Translational Medicine, 2021, e10253.
3) Dhar, N.; Arsiwala, A.; Murali, S.; Kane, R. S. “ “Trim”ming PolyQ Proteins with Engineered PML”, Biotechnology and Bioengineering, 2020, 117, 2, 362-371. Selected as an “Editor’s Choice” article.
4) Rosenbloom, A.; Kane, R. S.; Bugaj, L.; Schaffer, D. V.; “β-catenin Signaling Dynamics Regulate Cell Fate in Differentiating Neural Stem Cells”, Proceedings of the National Academy of Sciences, USA, 117, 46, 28828-28837.
5) Arsiwala, A.; Varner, C.; McCaffery, J. N.; Kell, A.; Pendyala, G.; Castro, A.; Hariharan, V.; Moreno, A.; Kane, R. S. “Nanopatterning Protein Antigens to Refocus the Immune Response”, Nanoscale, 2019, 11, 32, 15307-15311.
6) Mukherjee, A.; Dhar, N.; Stathos, M.; Schaffer, D.V.; Kane, R. S., “Understanding how Wnt influences destruction complex activity and β-catenin dynamics”, iScience, 2018, 6, 13-21.
7) S-J. Kwon, D. H. Na, J. H. Kwak, M. Douaisi, F. Zhang, E. J. Park, J-H. Park, H. Youn, C-S. Song, R. S. Kane, J.S. Dordick, K.B. Lee, R. J. Linhardt, “Nanostructured glycan architecture is important in the inhibition of influenza A virus infection” Nature Nanotechnology, 2017, 12, 48.
8) Cao, J.; Arha, M.; Sudrik, C.; Mukherjee,A.; Wu, X.; Kane, R. S., “A Universal Strategy for Regulating mRNA Translation in Prokaryotic and Eukaryotic Cells”, 2015, Nucleic Acids Research, 43, 8, 4353-62.
9) Bugaj, L. J.; Mesuda, C. K.; Varedi, M.; Kane, R. S.; Schaffer, D. V., “Regulation of Endogenous Transmembrane Receptors Through Optogenetic Cry2 Clustering”, Nature Communications, 2015, 6, Article number: 6898, doi:10.1038/ncomms7898.
10) Stanley, S. A.; Sauer, J.; Kane, R. S.; Dordick, J. S.; Friedman, J. M., “Remote Regulation of Glucose Homeostasis in Mice Using Genetically Encoded Nanoparticles”, Nature Medicine, 2015, 21, 1, 92-8.
11) Patke, S.; Boggara, M.; Maheshwari, R.; Srivastava, S. K.; Arha, M.; Douaisi, M.; Martin, J. M.; Harvey, I. B.; Brier, M.; Rosen, T.; Mogridge, J.; Kane, R. S., “Design of Monodisperse and Well-defined Polypeptide-based Polyvalent Inhibitors of Anthrax Toxin”, Angewandte Chemie International Edition, 2014, 53, 31, 8037-40.
12) Cao, J.; Arha, M.; Sudrik, C.; Schaffer, D. V.; Kane, R. S., “Bidirectional Regulation of mRNA Translation in Mammalian Cells Using PUF Domains”, Angewandte Chemie International Edition, 2014, 53, 19, 4900-4.
13) Mehta, K.K.; Paskaleva, E.E.; Azizi-Ghannad, S.; Dordick, J.S.; Kane, R.S. “Characterization of AmiBA2446, a novel bacteriolytic enzyme active against Bacillus anthracis,” Applied Environmental Microbiology, 2013, 79, 19, 5899-5906.
14) Conway, A.; Vazin, T.; Rode, N.; Healy, K. E.; Kane, R. S.; Schaffer, D.V. “Multivalent Ligands Control Stem Cell Behavior in vitro and in vivo”, Nature Nanotechnology, 2013, 8, 831-832.
15) Bugaj, L.J.; Choksi, A.T.; Mesuda, C.K.; Kane, R.S.; Schaffer, D.V. “Optogenetic protein clustering and signaling activation in mammalian cells,” Nature Methods, 2013, 10, 249-252.
16) Joshi, A., Kate, Sandesh., Mondal, D., Boggara, M.B., Saraph, A., Martin, J.T., McAlpine,R., Day, R., Garcia, A.E., Mogridge, J., R.S. Kane, “Structure-based Design of a Heptavalent Anthrax Toxin Inhibitor”, Biomacromolecules, 2011, 12, 3, 791-796.
17) Kane, R. S. “Thermodynamics of Multivalent Interactions: Influence of the Linker”, Langmuir, 2010, 26, 11, 8636-8640.
18) Joshi, A.; Punyani, S.; Bale, S. S.; Yang, H.; Borca-Tasçiuc, T.; Kane, R. S. 2007, “Nanotube-Assisted Protein Deactivation”, Nature Nanotechnology, 2008, 3, 41-45.
19) Rai, P. R.; Saraph, A.; Ashton, R.; Poon, V. ; Mogridge, J. ; Kane, R. S. “Raft-inspired Polyvalent Inhibitors of Anthrax Toxin: Modulating Inhibitory Potency by Formation of Lipid Microdomains”, Angewandte Chemie International Edition, 2007, 46, 2207
20) Rai, P.; Padala, C.; Poon, V.; Saraph, A.; Basha, S.; Kate, S.; Tao, K.; Mogridge, J.; Kane, R.S. “Statistical Pattern Matching Facilitates Neutralization of Anthrax Toxin”, Nature Biotechnology, 2006, 24, 582.
21) Basha, S.; Rai, P.; Poon, V.; Saraph, A.; Gujraty, K.; Go, M.; Sadacharan, S.; Frost, M.; Mogridge, J.; Kane, R. S. “Polyvalent Inhibitors of Anthrax Toxin that Target Host Receptors”, Proceedings of the National Academy of Sciences, USA, 2006, 103, 13509- 13513.
22) Chakrapani, N.; Wei, B.; Carrillo, A.; Ajayan, P. M.; Kane, R. S. “Capillarity Driven Assembly of Two-dimensional Cellular Carbon Nanotube Foams,” Proceedings of the National Academy of Sciences, USA, 2004, 101, 4009. Featured on the cover.
23) Kane, R. S.; Deschatelets, P.; Whitesides, G. M. “Kosmotropes Form the Basis of Protein Resistant Surfaces,” Langmuir, 2003, 19, 2388.
Complete List of Publications
159) Halfmann, P. J.; Frey, S. J.; Kuroda, M.; Armbrust, T.; Yang, J. E.; Wright, E. R.; Kawaoka, Y.; Kane R.S. “Multivalent S2-Based Vaccines Protect Hamsters Against SARS-CoV-2 and Elicit Broadly Cross-Reactive Antibodies to Endemic Coronaviruses” 2021, manuscript submitted.
158) Halfmann, P.; Castro, A.; Loeffler, K.; Frey, S. J.; Chiba, S.; Kawaoka, Y.; Kane R.S. “Potent Neutralization of SARS-CoV-2 Including Variants of Concern by Vaccines Presenting the Receptor-Binding Domain Multivalently from Nanoscaffolds.” Bioengineering & Translational Medicine, 2021, e10253.
157) Chiba, S.; Frey, S. J.; Halfmann, P. J.; Kuroda, M.; Maemura, T.; Yang, J.; Wright, E. R.; Kawaoka, Y.; Kane, R. S. “Multivalent Nanoparticle-Based Vaccines Protect Hamsters Against SARS-CoV-2 After a Single Immunization”, Communications Biology, 2021, 4, 597.
156) Castro, A.; Carreño, J. M.; Duehr, J.; Krammer, F.; Kane, R. S. “Refocusing the Immune Response to Selected Epitopes on a Zika Virus Protein Antigen by Nanopatterning”, Advanced Healthcare Materials 2021, 2002140.
155) Frey, S. J.; Varner, C.; Arsiwala, A.; Currier, M. G.; Moore, M. L.; Kane, R. S. “The Design of Vaccines based on the Shielding of Antigenic Site Ø of a Respiratory Syncytial Virus Fusion Protein Immunogen”, Advanced Healthcare Materials, 2021, 2000714. 10.1002/adhm.202000714.
154) Dhar, N.; Arsiwala, A.; Murali, S.; Kane, R. S. “ “Trim”ming PolyQ Proteins with Engineered PML”, Biotechnology and Bioengineering, 2020, 117, 2, 362-371. Selected as an “Editor’s Choice” article.
153) Rosenbloom, A.; Kane, R. S.; Bugaj, L.; Schaffer, D. V.; “b-catenin Signaling Dynamics Regulate Cell Fate in Differentiating Neural Stem Cells”, Proceedings of the National Academy of Sciences, USA, 117, 46, 28828-28837.
152) Mukherjee, A.; Sudrik, C. M.; Hu, Y.; Arha, M.; Stathos, M. E.; Schaffer, D. V.; Kane, R. S. “CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics”, ACS Synthetic Biology, 2020, 9, 9, 2274-2281.
151) Repina, N. A.; Johnson, H. J.; McClave, T.; Kane, R. S.; Schaffer, D. V. “Protocol to Fabricate Engineering Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics”, STAR Protocols, 2020, 100141.
150) Mukherjee, A.; Stathos, M. E.; Varner, C.; Arsiwala, A.; Frey, S.; Hu, Y.; Schaffer, D. V.; Kane, R. S. “One-pot Synthesis of Heterodimeric Agonists that Robustly Activate the Canonical Wnt Signaling Pathway”, Chemical Communications, 2020, 56, 25, 3685-3688.
149) Hariharan, V.; Kane, R. S. “Glycosylation as a Tool for Rational Vaccine Design”, Biotechnology and Bioengineering, 2020, 117, 8, 2556-2570.
148) Repina, N.A.; McClave, T.; Johnson, H. J.; Bao, X.; Kane, R. S.; Schaffer, D. V. “Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics”, Cell Reports, 2020, 31, 10, 107737.
147) Wang, J.; Min, J.; Eghtesadi, S. A.; Kane, R. S.; Chilkoti, A. “A Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density”, ACS Nano, 2020, 14, 1, 372-383.
146) Frey, S.; Hoffman, A. S.; Hubbell, J. A.; Kane, R. S. “Surface-Immobilized Biomolecules”, in Biomaterials Science, 4th Ed.; Ed: R. Wagner, S. E. Sakiyama-Elbert, G. Zhang, M. J. Yaszemski, 2020, 539-551.
145) Arsiwala, A.; Varner, C.; McCaffery, J. N.; Kell, A.; Pendyala, G.; Castro, A.; Hariharan, V.; Moreno, A.; Kane, R. S. “Nanopatterning Protein Antigens to Refocus the Immune Response”, Nanoscale, 2019, 11, 32, 15307-15311.
144) Arsiwala, A.; Castro, A.; Frey, S.; Stathos, M.; Kane, R. S., “Designing Multivalent Ligands to Control Biological Interactions: From Vaccines and Cellular Effectors to Targeted Drug Delivery”, Chemistry – An Asian Journal, 2019, 14, 2, 244-255.
143) Julian, M. C.; Rabia, L. A.; Desai, A. A.; Arsiwala, A.; Gerson, J. E.; Paulson, H. L.; Kane, R. S.; Tessier, P. M. “Nature-inspired design and evolution of anti-amyloid antibodies”, Journal of Biological Chemistry, 2019, 294, 21, 8438-8451.
142) Park, J. H.; Dumani, D. S.; Arsiwala, A.; Emelianov, S.; Kane, R. S., “Tunable aggregation of gold-silica janus nanoparticles to enable contrast-enhanced multiwavelength photoacoustic imaging in vivo”, Nanoscale, 2018, 10 (32), 15365-15370.
141) Mukherjee, A.; Dhar, N.; Stathos, M.; Schaffer, D.V.; Kane, R. S. “Understanding how Wnt influences destruction complex activity and β-catenin dynamics”, iScience, 6, 13-21.
140) Martin, J; Douaisi, M.; Arsiwala, A.; Arha, M.; Kane, R. S. “Synthesis of multivalent polymer-aptamer conjugates with enhanced inhibitory potency”, International Journal of Nanomedicine, 2018, 13, 5249.
139) Frey,S.; Castro, A.; Arsiwala, A.; Kane, R. S. “Bionanotechnology for Vaccine Design”, Current Opinion in Biotechnology, 2018, 52, 80-88.
138) Kwon, S-J.; Na, D. H.; Kwak, J. H.; Douaisi, M.; Zhang, F.; Park, E. J.; Park, J-H.; Youn, H.; Song, C-S.; Kane, R. S.; Dordick, J. S.; Lee, K-B.; Linhardt, R. J., “Nanostructured glycan architecture is important in the inhibition of influenza A virus infection” Nature Nanotechnology, 2017, 12, 48.
137) Repina, N. A.; Rosenbloom, A.; Mukherjee, A.; Schaffer, D.V.; Kane, R. S., “At Light Speed: Advances in Optogenetic Systems for Regulating Cell Signaling and Behavior”, Annual Review of Chemical and Biomolecular Engineering, 2017, 8, 13.
136) Mukherjee, A.; Repina, N. A.; Schaffer, D. V.; Kane, R. S., “Optogenetic Tools for Cell Biological Applications,” Journal of Thoracic Diseases, 2017, 8, 1, 87.
135) Wu, X.; Kwon, S.J.; Kim, J.; Kane, R. S.; Dordick, J. S., “Biocatalytic Nanocomposites for Combating Bacterial Pathogens,” Annual Review of Chemical and Biomolecular Engineering, 2017, 8, 1, 87.
134) Mehta, K. K.; Paskaleva, E. E.; Wu, X.; Grover, N.; Mundra, R. V.; Chen, K.; Zhang, Y.; Yang, Z.; Feng, H.; Dordick, J. S.; Kane, R. S., “Newly identified bacteriolytic enzymes that target a wide range of clinical isolates of Clostridium Difficile, ” Biotechnology & Bioengineering, 2016, 113, 12, 2568-2576.
133) Wu, X.; Paskaleva, E. E.; Mehta, K. K.; Dordick, J. S.; Kane, R. S., “Wall Teichoic Acids Are Involved in the Medium-Induced Loss of Function of the Autolysin CD11 against Clostridium difficile,” Scientific Reports, 2016, 6, 35616.
132) Choi, I.S.; Kane, R. S.; Xu, B., “Nanobiointerfaces: Interfaces Between Biological Entities and Nanomaterials,” CHEMNANOMAT, 2016, 2, 5, 321-322.
131) Bugaj, L. J.; Mesuda, C. K.; Varedi, M.; Kane, R. S.; Schaffer, D. V., “Regulation of Endogenous Transmembrane Receptors Through Optogenetic Cry2 Clustering”, Nature Communications, 2015, 6, Article number: 6898, doi:10.1038/ncomms7898.
130) Stanley, S. A.; Sauer, J.; Kane, R. S.; Dordick, J. S.; Friedman, J. M., “Remote Regulation of Glucose Homeostasis in Mice Using Genetically Encoded Nanoparticles”, Nature Medicine, 2015, 21, 1, 92-8.
129) Cao, J.; Arha, M.; Sudrik, C.; Mukherjee,A.; Wu, X.; Kane, R. S., “A Universal Strategy for Regulating mRNA Translation in Prokaryotic and Eukaryotic Cells”, 2015, Nucleic Acids Research, 43, 8, 4353-62.
128) Paskaleva, E. E.; Mundra, R. V; Mehta, K. K.; Pangule, R. C.; Glatfelter, W. S.; Chen, Z.; Wu, X.; Dordick, J. S.; Kane, R. S., “Binding Domains of Bacillus anthracis Phage Endolysins Recognize Cell Culture Age related Features on the Bacterial Surface”, Biotechnology Progress, 2015, 31, 1487-1493.
127) Wu, X.; Grover, N.; Paskaleva, E. E.; Mundra, R. V.; Page, M. A.; Kane, R. S.; Dordick, J. S., “Characterization of the Activity of the Spore Cortex Lytic Enzyme CwlJ1”, Biotechnology and Bioengineering, 2015, 112, 7, 1365-75.
126) Varner, C. T.; Rosen, T.; Martin, J. T.; Kane, R. S., “Recent Advances in Engineering Polyvalent Biological Interactions”, Biomacromolecules, 2015, 16, 1, 43-55.
125) Lao, M. C.; Wu, X.; Page, M. A.; Paskaleva, E. E.; Arnett, C.; Boyd, A.; Setlow, P.; Kane, R. S.; Dordick, J. S., “Cortex-Lytic Activity of Endogenous CwlJ on Decoated Bacterial Spores”, manuscript submitted.
124) Patke, S.; Boggara, M.; Maheshwari, R.; Srivastava, S. K.; Arha, M.; Douaisi, M.; Martin, J. M.; Harvey, I. B.; Brier, M.; Rosen, T.; Mogridge, J.; Kane, R. S., “Design of Monodisperse and Well-defined Polypeptide-based Polyvalent Inhibitors of Anthrax Toxin”, Angewandte Chemie International Edition, 2014, 53, 31, 8037-40.
123) Cao, J.; Arha, M.; Sudrik, C.; Schaffer, D. V.; Kane, R. S., “Bidirectional Regulation of mRNA Translation in Mammalian Cells Using PUF Domains”, Angewandte Chemie International Edition, 2014, 53, 19, 4900-4.
122) Singh, A.; Mehta, M.; Worley, K.; Dordick, J.; Kane, R.; Wan, L., “Carbon Nanotubes Induced Loss of Multicellular Chirality on Micropatterned Substrate is Mediated by Oxidative Stress”, ACS Nano, 2014, 8, 3, 2196-2205.
121) Grover, N.; Paskaleva, E.; Mehta, K.M.; Dordick, J. S.; Kane, R. S., “Growth Inhibition Of Mycobacterium smegmatis by mycobacteriophage-derived enzymes“, Enzyme and Microbial Technology, 2014, 63, 1-6.
120) Vazin, T.; Ashton, R. S.; Conway, A.; Rode, N.; Lee, S. M.; Bravo, V.; Healy, K. E.; Kane, R. S.; Schaffer, D. V., “The Effect of Multivalent Sonic Hedgehog on Differentiation of Human Embryonic Stem Cells into Dopaminergic and GABAergic Neurons”, Biomaterials, 2014, 35, 3, 941-948.
119) Mundra, R. V.; Wu, X.; Sauer, J.; Dordick, J. S.; Kane, R. S., “Nanotubes in Biological Applications“, Current Opinion in Biotechnology, 2014, 28, 25-32.
118) Conway, A.; Vazin, T.; Rode, N.; Healy, K. E.; Kane, R. S.; Schaffer, D.V. “Multivalent Ligands Control Stem Cell Behavior in vitro and in vivo”, Nature Nanotechnology, 2013, 8, 831-832.
117) Bugaj, L.J.; Choksi, A.T.; Mesuda, C.K.; Kane, R.S.; Schaffer, D.V. “Optogenetic protein clustering and signaling activation in mammalian cells,” Nature Methods, 2013, 10, 249-252.
116) Sudrik, C.; Arha, M.; Cao, J.; Schaffer, D.V.; Kane, R.S. “Translational repression using BIV Tat peptide–TAR RNA interaction in mammalian cells,” Chemical Communications, 2013, 49, 7457-7459.
115) Cao, J.; Arha, M.; Sudrik, C.; Bugaj, L.J.; Schaffer, D.V.; Kane, R.S. “Light-inducible activation of target mRNA translation in mammalian cells,” Chemical Communications, 2013, 49, 8338-8340.
114) Srinivasan, S.; Patke, S.; Wang, Y.; Ye, Z.; Litt, J.; Srivastava, S.K.; Lopez, M.M.; Kane, R.S.; Colón, W. “Pathogenic SAA1.1 Exhibits a Slower Fibrillation Kinetics and Different Amyloid Morphology than Non-pathogenic SAA2.2,” Journal of Biological Chemistry, 2013, 288, 4, 2744-2755.
113) Boggara, M.; Athmakuri, K.; Srivastava, S.; Cole, R.; Kane, R.S. “Characterization of the diffusion of epidermal growth factor receptor clusters by single particle tracking,” Biochimica et Biophysica Acta–Biomembranes, 2013, 1828, 2, 419-426.
112) Solanki, K.; Grover, N.; Downs, P.; Paskaleva, E.E.; Mehta, K.K.; Lee, L.; Schadler, L.S.; Kane, R.S.; Dordick, J.S. “Enzyme-based listericidal nanocomposites,” Scientific Reports, 2013, 3, 1584.
111) Lotz, S.; Goderie, S.; Tokas, N.; Hirsch, S.E.; Ahmad, F.; Corneo, B.; Le, S.; Banerjee, A.; Kane, R.S.; Stern, J.H.; Temple, S.; Fasano, C.A. “Sustained Levels of FGF2 Maintain Undifferentiated Stem Cell Cultures with Biweekly Feeding,” PLoS ONE, 2013, 8(2) e56289.
110) Patke, S.; Srinivasan, S.; Maheshwari, R.; Srivastava, S.K.; Aguilera, J.J.; Colón, W.; Kane, R.S. “Characterization of the Oligomerization and Aggregation of Human Serum Amyloid A,” PLoS ONE, 2013, 8(6) e64974.
109) Mehta, K.K.; Paskaleva, E.E.; Azizi-Ghannad, S.; Dordick, J.S.; Kane, R.S. “Characterization of AmiBA2446, a novel bacteriolytic enzyme active against Bacillus anthracis,” Applied Environmental Microbiology, 2013, 79, 19, 5899-5906.
108) Mundra, R.V.; Mehta, K.K.; Wu, X.; Paskaleva, E.E.; Kane, R.S.; Dordick, J.S. “Enzyme-Driven Bacillus Spore Coat Degradation Leading to Spore Killing,” Biotechnology and Bioengineering, 2013, 111, 4, 654-663.
107) Mehta, K.K.; Paskaleva, E.E.; Dordick, J.S.; Kane, R.S. “Carbon Nanotubes in Biomedical Applications,” 2013, Handbook of Nanobiomedical Research, Volume I, Chapter 12.
106) Grover, N.; Douaisi, M.P.; Borkar, I.V.; Lee, L.; Dinu, C.Z.; Kane, R.S.; J.S.Dordick. “Perhydrolase-nanotube paint composites with sporicidal and antiviral activity,” Applied Microbiology and Biotechnology, 2013, 97, 8813-8821.
105) Martin, J. T.; Kane, R. S. “Design of Polyvalent Polymer Therapeutics,” Book chapter in Functional Polymers by Post-Polymerization Modification.; 2012, Ed: P. Theato, H. Klok, Chapter Eleven, pp 267-290.
104) Banerjee, I.; Mehta, K. K.; Dordick, J. S.; Kane, R. S. “Light-activated porphyrin-based formulations to inactivate bacterial spores,” Journal of Applied Microbiology, 2012, 113, 6, 1461-1467.
103) Patke, S.; Maheshwari, R.; Litt, J.; Srinivasan, S.; Aguilera, J. J.; Colón, W.; Kane, R. S. “Influence of the Carboxy-Terminus of Serum Amyloid A on Protein Oligomerization, Misfolding, and Aggregation”, Biochemistry, 2012,51, 14, 3092–3099.
102) Ladiwala, A. R. A.; Litt, J.; Kane, R. S.; Aucoin, D. S.; Smith, S. O.; Ranjan, S.; Davis, J.; Van Nostrand, W. E.; Tessier, P. M. “Conformational Differences between Two Amyloid β Oligomers of Similar Size and Dissimilar Toxicity,” The Journal of Biological Chemistry, 2012, 287, 29, 24765–24773.
101)Grover, N., Borkar, I. V., Dinu, C. Z., Kane, R. S., J. S. Dordick, Enzyme and Microbial Technology, 2012, 50, 6-7, 271-279.
100) Lowry, N.; Goderie, S. K.; Lederman, P.; Charniga, C.; Gooch, M. R.; Gracey, K. D.; Banerjee, A.; Punyani, S.; Silver, J.; Kane, R. S.; Stern, J.H.; Temple, S. “Long-Term Release of Shh from Implanted Biodegradable Microspheres Significantly Improves Recovery from Spinal Cord Injury in Mice”, Biomaterials, 2012, 33, 10, 2892-2901.
99) Banerjee, I., Douaisi, M. P., Mondal, D., R. S. Kane “Light-Activated Nanotube-Porphyrin Conjugates as Effective Antiviral Agents”, Nanotechnology, 2012, 23, 105101.
98) Dinu, C. Z., Borkar, I. V., Bale, S. S., Campbell, A., Kane, R. S., J. S. Dordick, , Journal of Molecular Catalysis B: Enzymatic, 2012, 75, 20-26.
97) Joshi, A., Kate, Sandesh., Mondal, D., Boggara, M.B., Saraph, A., Martin, J.T., McAlpine,R., Day, R., Garcia, A.E., Mogridge, J., R.S. Kane, “Structure-based Design of a Heptavalent Anthrax Toxin Inhibitor, Biomacromolecules, 2011, 12, 3, 791-796.
96) Shah, D. A., Kwon, S. J., Bale, S. S., Banerjee, A., Dordick, J. S., R.S. Kane, “Regulation of Stem Cell Signaling by Nanoparticle-Mediated Intracellular Protein Delivery”, Biomaterials, 2011, 32, 12, 3210-9.
95) Miao, J., Pangule, R. C., Paskaleva, E. E., Hwang, E. E., Kane, R. S., Linhardt, R. J., J. S. Dordick, “Lysostaphin-functionalized cellulose fibers with antistaphylococcal activity for wound healing applications”, Biomaterials, 2011, 32, 36, 9557-9567.
94) Banerjee, I.; Pangule, R. C.; R.S. Kane, “Antifouling Coatings: Recent Developments in the Design of Surfaces that Prevent Fouling by Proteins, Bacteria, and Marine Organisms”, Advanced Materials, 2011, 23, 6, 690-718.
93) Kane, R. S. “Thermodynamics of Multivalent Interactions: Influence of the Linker”, Langmuir, 2010, 26, 11, 8636-8640.
92) Dinu, C. Z.; Borkar, I. V.; Bale, S. S.; Zhu, G.; Sanford, K.; Whited, G.; Kane, R. S.; Dordick, J.S., Green Polymer Chemistry: Biocatalysis and Biomaterials, 2010, Chapter 8, 103-107.
91) Banerjee, I., D. Mondal, J. Martin, R. S. Kane, “Photoactivated Antimicrobial Activity of Carbon Nanotube-Porphyrin Conjugates”, Langmuir, 2010, 26, 22, 17369-17374.
90) Bale, S. S.; Kwon, S. J.; Shah, D. A.; Banerjee, A.; Dordick, J. S.; R. S. Kane, “Nanoparticle-Mediated Cytoplasmic Delivery of Proteins to Target Cellular Machinery”, ACS Nano, 2010, 4, 3, 1493-1500.
89) Pangule, R. C.; Brooks, S. J.; Dinu, C. Z.; Bale, S. S.; Salmon, S.L.; Zhu, G.; Metzger, D. W.; Kane, R. S.; Dordick, J. S. “Antistaphylococcal Nanocomposite Films Based on Enzyme-Nanotube Conjugates”, ACS Nano, 2010, 4, 7, 3993-4000.
88) Athmakuri, K.; Rohovie, M.; Padala, C.; Cole, R.; R. S. Kane, “Influence of Chain Length on the Diffusion and Electrophoresis of DNA Adsorbed on Heterogeneous Supported Lipid Bilayers”, Langmuir, 2010, 26, 16, 13393-13398.
87) Dinu, C. Z.; Zhu, G.; Bale, S. S.; Anand G.; Reeder, P. J.; Sanford, K.; Whited, G.; Kane, R.S.; J.S. Dordick, Advanced Functional Materials, 2010, 20, 3, 392-398.
86) Jang, J-H.; Koerber, J. T.; Gujraty, K.; Bethi, S. R.; Kane, R. S.; D.V. Schaffer, “Surface Immobilization of Hexa-Histidine-Tagged Adeno-Associated Viral Vectors for Localized Gene Delivery”, Gene Therapy, 2010, 17, 1384-1389
85) Athmakuri, K.; Padala, C.; Litt, J.; Cole, R.; Kumar, S.; R.S. Kane, “Controlling DNA Adsorption and Diffusion on Lipid Bilayers by the Formation of Lipid Domains”, Langmuir, 2010, 26, 1, 397-401.
84) Borkar, I. V.; Dinu, C. Z.; Zhu, G.; Kane, R. S.; J.S. Dordick, Biotechnology Progress, 2010, 26, 6, 1622-1628.
83) Bale, S. S.; Kwon, S. J.; Shah, D. A.; Kane, R. S.; Dordick, J. S. “A GFP Complementation System for Monitoring and Directing Nanomaterial Mediated Protein Delivery to Human Cellular Organelles”, Biotechnology & Bioengineering, 2010, 107, 6, 1040-1047.
82) Gupta, A.; Kane, R. S.; D-A. Borca-Tasciuc, “Local Temperature Measurement in the Vicinity of Electromagnetically-Heated Magnetite and Gold Nanoparticles”, Journal of Applied Physics, 2010, 108, 064901.
81) Kesapragada, S. V.; Yim, T-J.; Dordick, J. S.; Kane, R. S.; D. Gall, Journal of Nanoscience and Nanotechnology, 2010, 10, 3, 2252-56.
80) Banerjee, A.; Arha, M.; Choudhary, S.; Ashton, R. S.; Bhatia, S. R.; Schaffer, D. V.; Kane, R. S. “The Influence of Hydrogel Modulus on the Proliferation and Differentiation of Encapsulated Neural Stem Cells”, Biomaterials, 2009, 30, 27, 4695-4699.
79) Herce, H.D.; Garcia, A. E.; Litt, J.; Kane, R. S.; Martin, P.; Enrique, N.; Rebolledo, A.; Milesi, V. “Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell Penetrating Peptides”, Biophysical Journal, 2009, 97, 7, 1917-25.
78) Litt, J.; Padala, C.; Asuri, P.; Vutukuru, S.; Athmakuri, K.; Kumar, S.; Dordick, J.; Kane, R. S.; “Enhancing Protein Stability by Adsorption onto Raft-Like Lipid Domains”, 2009, Journal of the American Chemical Society, 2009, 131, 7107-11.
77) Sriram, S. M.; Kane, R. S.; Kwon, Y. T., Chemistry and Biology, 2009, 16, 2, 121-131.
76) Barua, S.; Joshi, A.; Banerjee, A.; Matthews, D.; Sharfstein, S. T.; Cramer, S. M.; Kane, R. S.; Rege, K., Molecular Pharmaceutics, 2009, 6, 86-97.
75) Vance, D.; Martin, J.; Patke, S.; Kane, R. S. “The Design of Polyvalent Scaffolds for Targeted Delivery”, Advanced Drug Delivery Reviews, 2009, 61, 11, 931-9.
74) Pangule, R. C.; Bale, S. S.; Shah, D. A.; Joshi, A.; Asuri, P.; Dordick, J. S.; Kane, R. S., Biological Interactions on Materials Surfaces: Understanding and Controlling Protein, Cell and Tissue Responses, Springer Science+Business Media, 2009, 98-113.
73) Joshi, A.; Punyani, S.; Bale, S. S.; Yang, H.; Borca-Tasçiuc, T.; Kane, R. S., “Nanotube-Assisted Protein Deactivation”, Nature Nanotechnology, 2008, 3, 41-45.
72) Kane, R. S. “Fabricating complex polymeric micro- and nanostructures: Lithography in microfluidic devices”, Angewandte Chemie International Edition, 2008, 47, 8, 1368-1370.
71) Rai, P.; Vance, D.; Poon, V.; Mogridge, J.; Kane, R. S. “Stable and Potent Polyvalent Anthrax Toxin Inhibitors: Raft-inspired Domain Formation in Liposomes Containing PEGylated Lipids”, Chemistry – A European Journal, 2008, 14, 26, 7748-7751.
70)Vance, D.; Shah, M.; Joshi, A.; Kane, R. S. “Polyvalency: A Promising Strategy for Drug Design”, Biotechnology & Bioengineering, 2008, 101, 3, 429-434.
69) Joshi, A.; Vance, D.; Rai, P.; Thiyagarajan, A.; Kane, R. S. “The Design of Polyvalent Therapeutics”, Chemistry – A European Journal, 2008, 14, 26, 7738-7747.
68) Vutukuru, S.; Kane, R. S. “Surface Plasmon Resonance Spectroscopy-Based High-Throughput Screening of Ligands for use in Affinity and Displacement Chromatography”, Langmuir, 2008, 24, 20, 11784-11789.
67) Vutukuru, S.; Kate, S. D.; McCallum, S. A.; Morrison, C. J.; Cramer, S.M.; Kane, R. S., Langmuir, 2008, 24, 13, 6768-6778.
66) Shah, D.; Pangule, R. C.; Bale, S. S.; Asuri, P.; Joshi, A.; Banerjee, A.; Vance, D.; Dordick, J. S.; Kane, R. S., Methods in Bioengineering: Nanoscale Bioengineering and Nanomedicine, 2008, 1-23.
65) Li, X.; Chen, H.; Khan, A. A.; Lauterbach, S. B.; Lanzillotti, R.; Rai, P. R.; Kane, R. S.; Coetzer, T. L.; Chishti, A. H. “Receptor-Based Identification of an Inhibitory Peptide Against Blood Stage Malaria”, Biochemical and Biophysical Research Communications, 2008, 376, 3, 489-93.
64) Gujraty, K. V.; Yanjarappa, M. J.; Saraph, A.; Joshi, A.; Mogridge, J. ; Kane, R. S., Journal of Polymer Science, Part A: Polymer Chemistry, 2008, 46, 21, 7249-7257.
63) Rai, P. R.; Saraph, A.; Ashton, R.; Poon, V.; Mogridge, J.; Kane, R. S. “Raftlike Polyvalent Inhibitors of the Anthrax Toxin: Modulating Inhibitory Potency by Formation of Lipid Microdomains,” Angewandte Chemie International Edition, 2007, 46, 2207.
62) Kaur, S; Sahoo, S.; Ajayan, P.; Kane, R. S. “Capillarity-Driven Assembly of Carbon Nanotubes on Substrates into DenseVertically Aligned Arrays”, Advanced Materials, 2007, 19, 2984.
61) Asuri, P.; Karajanagi, S. S.; Kane, R. S.; Dordick, J. S. “Polymer-Nanotube-Enzyme Composites as Active Antifouling Films”, Small, 2007, 3, 50-53. Highlighted in Nature Nanotechnology.
60) Kane, R. S.; Stroock, A. D. “Nanobiotechnology: Protein-Nanomaterial Interactions,” Biotechnology Progress, 2007, 23, 316-319.
59) Koerber, J. T.; Jang, J-H.; Yu, J. H.; Kane, R. S.; Schaffer, D. V. “Engineering Adeno-Associated Virus for One-Step Purification via Immobilized Metal Affinity Chromatography,” Human Gene Therapy, 2007, 18, 367-378.
58) Ashton, R. S.; Peltier, J.; Fasano, C.; O’Neill, A.; Leonard, J.; Temple, S.; Schaffer, D. V.; Kane, R. S. “Clonal Microarrays: High-Throughput Screening of Gene Function in Stem Cells”, Stem Cells, 2007, 25, 2928.
57) Bale, S. S.; Asuri, P.; Karajanagi, S. S.; Dordick, J. S.; Kane, R. S. “Protein-Directed Formation of Silver Nanoparticles on Carbon Nanotubes”, Advanced Materials, 2007, 19, 20, 3167.
56) Asuri, P.; Bale, S. S.; Pangule, R. C.; Shah, D. A.; Kane, R. S.; Dordick, J. S., Langmuir, 2007, 23, 24, 12318.
55) Ashton, R. S.; Banerjee, A.; Punyani, S.; Schaffer, D. V.; Kane, R. S. “Scaffolds based on Degradable Alginate Hydrogels and Poly (lactide-co-glycolide) Microspheres for Stem Cell Culture”, Biomaterials, 2007, 28, 36, 5518.
54) Suhr, J.; Joshi, A..; Schadler, L.; Kane, R. S.; Koratkar, N. A., Journal of Nanoscience and Nanotechnology, 2007, 7, 1684-1687.
53) Asuri, P.; Karajanagi, S. S.; Dordick, J. S.; Kane, R. S., Journal of Nanoscience and Nanotechnology, 2007, 7, 1675-1678.
52) Rai, P.; Padala, C.; Poon, V.; Saraph, A.; Basha, S.; Kate, S.; Tao, K.; Mogridge, J.; Kane, R. S. “Statistical Pattern Matching Facilitates the Design of Polyvalent Inhibitors of Anthrax and Cholera Toxins”, Nature Biotechnology, 2006, 24, 582.
51) Basha, S.; Rai, P.; Poon, V.; Saraph, A.; Gujraty, K.; Go, M.; Sadacharan, S.; Frost, M.; Mogridge, J.; Kane, R. S. “Polyvalent Inhibitors of Anthrax Toxin that Target Host Receptors”, Proceedings of the National Academy of Sciences, USA, 2006, 103, 13509.
50) Kane, R. S. “Polyvalency: Recent Developments and New Opportunities for Chemical Engineers”, AIChE Journal, 2006, 52, 3638.
49) Padala, C.; Cole, R.; Kumar, S.; Kane, R. S. “Lipid Mobility Controls the Diffusion of Small Biopolymer Adsorbates”, Langmuir, 2006, 22, 6750.
48) Zhang, W.; Joshi, A.; Wang, Z.; Kane, R. S.; Koratkar, N., Nanotechnology, 2007, 185703.
47) Gujraty, K.; Ashton, R.; Reddy, B. S.; Kate, S.; Faulkner, C. J.; Jennings, K.; Kane, R. S., Langmuir, 2006, 22, 10157.
46) Vutukuru, S; Reddy, B. S.; Kane, R. S., Langmuir, 2006, 22, 10152.
45) Kaur, S.; Ajayan, P.; Kane, R.S. “Design and Characterization of Three-dimensional Carbon Nanotube Foams”, Journal of Physical Chemistry B, 2006, 110, 21377.
44) Asuri, P.; Karajanagi, S. S.; Kane, R. S.; Dordick, J. S. “Increasing Protein Stability Through Control of the Nanoscale Environment”, Langmuir, 2006, 22, 5833.
43) Joshi, A.; Saraph, A.; Poon, V.; Mogridge, J.; Kane, R. S. “Potent Inhibitors of Anthrax Toxin based on Poly-L-Glutamic Acid”, Bioconjugate Chemistry, 2006, 17, 1265.
42) Asuri, P.; Bale, S. S.; Karajanagi, S. S.; Kane, R. S. “The Protein/Nanomaterial Interface”, Current Opinion in Biotechnology, 17, 562(invited contribution).
41) Jiang, X.; Takayama, S.; Chapman, R. G.; Kane, R. S.; Whitesides, G. M. “Micro-Scale Patterning of Cells and Their Environment”, Book chapter in Principles of Tissue Engineering, 3rd Ed.; Ed: R. Lanza, R. Langer, J. Vacanti, in press.
40) Karajanagi, S. S.; Asuri, P.; Sellitto, E.; Eker, B.; Bale, S. S.; Kane, R. S.; Dordick, J. S. “Protein-Carbon Nanotube Conjugates”, ACS Symposium Series, accepted..
39) Gujraty, K. V.; Joshi, A.; Saraph, A.; Poon, V.; Mogridge, J.; Kane, R. S., Biomacromolecules, 2006, 7, 2082.
38) Yanjarappa, M. J.; Gujraty, K. V. ; Joshi, A. ; Saraph, A. ; Kane, R. S., Biomacromolecules, 2006, 7, 1665.
37) Asuri, P.; Karajanagi, S. S.; Sellitto, E.; Kim, D.-Y.; Kane, R. S.; Dordick, J. S., Biotechnology and Bioengineering, 2006, 95, 804-811.
36) Asuri, P.; Karajanagi, S. S.; Dordick, J. S.; Kane, R. S. “Directed Assembly of Carbon Nanotubes at Liquid-Liquid Interfaces: Nanoscale Conveyors for Interfacial Biocatalysis”, Journal of the American Chemical Society, 2006, 128, 1046.
35) Karajanagi, S. S.; Yang, H.; Asuri, P.; Sellitto, E.; Dordick, J. S.; Kane, R. S. “Protein-assisted Solubilization of Single-Walled Carbon Nanotubes”, Langmuir, 2006, 22, 1392.
34) Carrillo, A. et al. “Biofunctionalized Block Copolymer Nanoparticles Based on ROMP”, Journal of Polymer Science Part A: Polymer Chemistry, 2006, 44, 928-939.
33) Yim, T.; Liu, J.; Lu, Y.; Kane, R. S.; Dordick, J. S. “Highly Active and Stable DNAzyme-Carbon Nanotube Hybrids”, Journal of the American Chemical Society, 2005, 127, 12200.
32) Gujraty, K. et al. “Functional Characterization of Peptide-based Anthrax Toxin Inhibitors”, Molecular Pharmaceutics, 2005, 2, 367-372.
31) Carrillo, A. et al., Nanotechnology, 2005, 16, S416-S421.
30) Koratkar, N. et al., Applied Physics Letters, 2005, 87, 6, #063102
29) Chakrapani, N.; Wei, B.; Carrillo, A.; Ajayan, P. M.; Kane, R. S. “Capillarity Driven Assembly of Two-dimensional Cellular Carbon Nanotube Foams,” Proceedings of the National Academy of Sciences, USA, 2004, 101, 4009. Featured on the cover.
28) Karajanagi, S.; Vertegel, A.; Kane, R.S.; Dordick, J.S. “Structure and Function of Enzymes Adsorbed onto Single-Walled Carbon Nanotubes,” Langmuir, 2004, 20, 11594.
27) Carrillo, A.; Kane, R. S. “Block Copolymer Nanoparticles of Controlled Size Via ROMP”, Journal of Polymer Science Part A: Polymer Chemistry, 2004, 42, 3352.
26) Sethuraman, A.; Han, M.; Kane, R. S.; Belfort, G., Langmuir, 2004, 20, 7779.
25) Ashton, R.; Padala, C.; Kane, R. S. “Microfluidic Separation of DNA,” Current Opinion in Biotechnology, 2003, 14, 497 (invited contribution).
24) Carrillo, A.; Gujraty, K.; Kane, R. S. “Surfaces and Substrates” in Microarray Technology and its Applications, eds. D. Nicolau and U. Muller, Springer-Verlag, New York, 2005.
23) Carrillo, A.; Swartz, J. A.; Gamba, J. M.; Kane, R. S.; Chakrapani, N.; Wei, B.; Ajayan, P. M., Nano Letters, 2003, 3, 1437.
22) Chakrapani, N.; Curran, S.; Wei, B.; Ajayan, P. M.; Carrillo, A.; Kane, R. S., Journal of Materials Research, 2003, 18, 2515.
21) Yim, T-J.; Kim, D-Y.; Karajanagi, S. S.; Lu, T-M.; Kane, R. S.; Dordick, J. S., Journal of Nanoscience and Nanotechnology, 2003, 3, 479.
20) Ganesan, P. G. et al. Applied Physics Letters, 2003, 83, 16, 3302.
19) Ganesan, P. G.; Cui, G.; Ellis, A.; Kane, R. S.; Ramanath, G., Materials Science Forum, 2004, 426-432, 3487.
18) Han, M.; Sethuraman, A.; Kane, R. S.; Belfort, G., Langmuir, 2003, 19, 23, 9868.
17) Han, M.; Kane, R. S.; Goto, M.; Belfort, G., Macromolecules, 2003, 36, 4472.
16) Mourez, M.; Kane, R. S.; Mogridge, J.; Metallo, S. M.; Deschatelets, P.; Sellman, B. R.; Whitesides, G. M.; Collier, J. “Designing a Polyvalent Inhibitor of Anthrax Toxin,” Nature Biotechnology, 2001, 19, 958. Featured in Nature’s special online focus on bioterrorism.
15) Fuerstmann, M. J.; Deschatelets, P.; Kane, R. S.; Schwartz, A.; Kenis, P. J. A.; Deutch, J. M.; Whitesides, G. M. “Solving Mazes Using Microfluidic Networks,” Langmuir, 2003, 19, 4714. Featured in Nature’s News and Views in Brief.
14) Kane, R. S.; Deschatelets, P.; Whitesides, G. M. “ Kosmotropes Form the Basis of Protein-Resistant Surfaces,” Langmuir, 2003, 19, 2388.
13) Stroock, A.; Kane, R. S.; Weck, M.; Metallo, S. J.; Whitesides, G. M. “Synthesis of Free-standing Quasi-Two-Dimensional Polymers,” Langmuir, 2003, 19, 2466.
12) Metallo, S. M.; Kane, R. S.; Holmlin, R. E.; Whitesides, G. M. “Bifunctional Polymers Presenting Vancomycin and Fluorescein that Direct Anti-Fluorescein Antibodies to Self assembled Monolayers Presenting D-Alanine-D-Alanine Groups,” Journal of the American Chemical Society, 2003, 125, 4534.
11) Kane, R. S., Jeon, N. L., Stroock, A., Ingber, D. E., Whitesides, G. M. “Microfluidics,” in Optical Biosensors, Eds. Ligler, Rowe-Taith, 571, 2002.
10) Kane, R. S., Glink, P. T., Chapman, R. G., McDonald, C., Jensen, P., Gao, H., Pasa-Tolic, L., Smith, R. D., Whitesides, G. M. “Study of the Basicity of the Amino Groups of the Aminoglycoside Amikacin using Capillary Electrophoresis,” Analytical Chemistry, 2001, 73, 4028.
9) Chiu, D. T.; Jeon, N. L.; Huang, S.; Kane, R. S.; Wargo, C. J.; Choi, I. S.; Ingber, D. E.; Whitesides, G. M. “Patterned Deposition of Cells and Proteins onto Surfaces by Using Three-dimensional Microfluidic Systems,” Proceedings of the National Academy of Sciences, USA, 2000, 97, 2408.
8) Ostuni, E.; Kane, R. S.; Chen, C. S.; Ingber, D.E.; Whitesides, G. M. “Patterning Mammalian Cells Using Elastomeric Membranes,” Langmuir, 2000, 16, 7811.
7) Joly, S. et al., “Multilayer Nanoreactors for Metallic and Semiconducting Particles,” Langmuir, 2000, 16, 1354.
6) Kane, R. S.; Takayama, S.; Ostuni, E.; Ingber, D. E.; Whitesides, G. M. “Patterning Proteins and Cells Using Soft Lithography,” Biomaterials, 1999, 20, 2363.
5) Takayama, S; Chapman, R. G.; Kane, R. S.; Whitesides, G. M. “Applications of Soft Lithography for Patterning of Cells and Their Environment,” Book chapter in Principles of Tissue Engineering, 2nd Ed.; Ed: R. Lanza, R. Langer, J. Vacanti.
4) Kane, R. S.; Cohen, R. E.; Silbey, R. “Semiconductor Nanocluster Growth within Polymer Films,” Langmuir, 1999, 15, 39.
3) Kane, R.S.; Cohen, R. E.; Silbey, R. “Synthesis of Doped ZnS Nanoclusters within Block Copolymer Nanoreactors,” Chemistry of Materials, 1999, 11, 90.
2) Kane, R. S.; Cohen, R. E.; Silbey, R. “Synthesis of PbS Nanoclusters within Block Copolymer Nanoreactors,” Chemistry of Materials, 1996, 8, 1919.
1) Kane, R. S.; Cohen, R. E.; Silbey, R. “Theoretical Study of the Electronic Structure of PbS Nanoclusters,” Journal of Physical Chemistry, 1996, 100, 7928.