Due to the active nonlinear feedback by outer hair cells (OHC), the cochlea is not only a sensor that convert an acoustic stimulus into an electrical signal delivered to the brain. The cochlea can also emit sounds, that can be measured in the ear canal. These sounds, called otoacoustic emissions (OAEs), can be used as a noninvasive and objective tool to determine the health of the cochlea and to learn about the biophysics and physiology of the cochlea.
In this work, we are coupling models for the middle ear mechanics to the cochlear model to simulate the emission of sounds by the cochlea. This research improve our understanding of otoacoustic emissions, active cochlear mechanics and could result in better diagnostic of hearing loss using otoacoustic emissions.
Publications:
- H., Meaud, J., 2022, Link between stimulus frequency otoacoustic emission peaks and cochlear resonances, Journal of the Acoustical Society of America, 151(3):1875:1894
- Bowling, T., Wen, H., Meenderink, S.W.F., Dong, W., Meaud, J., 2021, Intracochlear distortion products are broadly generated by outer hair cells but their contributions to otoacoustic emissions are spatially restricted, Scientific reports, 11(1):1-14
- Bowling, T., Lemons, C., Meaud, J., 2019, Reducing tectorial membrane viscoelasticity enhances spontaneous otoacoustic emissions and compromises the detection of low level sound, Scientific Reports, 9: 7494
- Wen, H., Bowling, T., Meaud, J., 2018, Investigation of the 2f1−f2 and 2f2−f1 distortion product otoacoustic emissions using a computational model of the gerbil ear, Hearing Research, 365:127-140
- Bowling, T., Meaud, J., 2018, Forward and reverse waves: modeling distortion products in the intracochlear fluid pressure, Biophysical Journal, 114(3):747:757