Pathology Dynamics

ANA and BMES Conference Presentations

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From October 17th to the 23rd, members of the Laboratory for Pathology Dynamics presented their research at the BMES and ANA annual conferences. Presenters included graduate, undergraduate, and high school level lab members giving both poster and oral presentations. Congratulations to all of our presenters!

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ALZ Walk to End Alzheimer’s Disease 

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Dr. Cassie Mitchell’s research group, The Laboratory for Pathology Dynamics (Biomedical Engineering at Georgia Tech-Emory) had a wonderful time at the ALZ Walk to End Alzheimer’s Disease on October 13, 2018, at Kennesaw State University, Atlanta, GA.  The three mile ALZ Walk was one many held nationwide to fundraise for research supported by the Alzheimer’s Association.  This was one of the lab’s chosen community service projects for this semester–something Dr. Mitchell initiated to help build good research and community ties and “lab culture” by connecting the students with the patients and families for whom they are trying to help with their research projects in the lab.  Attached is a picture from the professional photographer that has the lab pictured with their sign at the ALZWalk (taken by TrueSpeedPhoto, but no copyright on it).   The Laboratory for Pathology Dynamics was thrilled to be able to raise money (about $1400) and do the walk together as a research lab to help give back and show their support for Alzheimer’s patients both inside and outside the research lab setting. The Laboratory for Pathology Dynamics was happy to give time and support back to the Alzheimer’s Research who recently funded them via the 2018 Alzheimer’s Association Research Grant to Promote Diversity.  Dr. Mitchell and her students are excited for the results to come out as they continue to quilt thousands or articles worth of disparate Alzheimer’s data into predictions that can expedite Alzheimer’s clinical success.

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New Lab Publication: Associative Increases in ALS Survival Duration With Bi-PAP Usage

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Congratulations to Nishad Khamankar, the first author of the highly anticipated bi-level positive airway pressure (Bi-PAP) for ALS. This paper was published in Frontiers in Neurology and examines the benefits of daily Bi-PAP and cough assist on the survival of ALS patients. This paper has helped move ALS care forward and our lab is very proud of Nishad for his work.

Download your copy here: https://www.frontiersin.org/articles/10.3389/fneur.2018.00578/full

 

BMES Abstracts Fall 2018

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Congratulations to all of our lab members who had abstracts accepted for poster presentations at the Fall 2018 BMES Conference.

Special congratulations to the Bi-PAP team for being selected for to give an oral presentation!

 

Poster Presentations

  • Biocuration: Improving Automation, Productivity, Accuracy and Quality Control
    • Authors: Joseph Murphy, Kathleen Jordan, Andrew Sedler, Keelie Denson, Cassie Mitchell
  • Systematic Analysis of the Topic Landscape of Aging and Alzheimer’s Disease Literature
    • Authors: Andrew Sedler, Cassie Mitchell
  • Dynamic Meta-Analysis Approach to In Silico Models of Temporal Multi-scalar Neurophysiology
    • Authors: Albert Lee, Stefano Travaglino, Cassie Mitchell
  • Informatics-based Literature Mapping to Expedite Research for Chronic Myeloid Leukemia
    • Authors: Nidhi Mehra, Andrew Sedler, Cassie Mitchell
  • Optimizing PEG “Feeding Tube” Intervention for ALS using Predictive Medicine
    • Authors: Leila Bond, Paulamy Ganguly, Nishad Khamankar, Nolan Mallet, Cassie Mitchell

 

Oral Presentation

  • Optimizing Bi-PAP Intervention for ALS using Predictive Medicine
    • Authors: Nishad Khamankar, Leila Bond, Paulamy Ganguly, Nolan Mallet, Cassie Mitchell

New Lab Publication: Complexity in ALS Survival Prediction

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This is the long awaited Pfohl 2018 et. al. article in Frontiers in Neuroinformatics, which used a machine learning model to predict and classify ALS clinical survival.  This paper showcases where our lab is headed in terms of potential complexity and machine learning approaches to predictive medicine.

This paper has an amazing string of successful co-authors who were all undergrad alums in the lab.  Stephen Pfohl is now an NSF fellow getting a PhD in Bioinformatics at Stanford, Renaid Kim is getting an MD-PhD at University of Michigan Medical Scientist Training Program, and Grant Coan is getting his MD at University of Texas at San Antonio.

Pfohl, S. R., et al. (2018). “Unraveling the Complexity of Amyotrophic Lateral Sclerosis Survival Prediction.” Frontiers in Neuroinformatics 12(36).