PICMOA (Pan-disease Classification in Mode of Action Protein Space) classifies 3,526 diseases across 20 clinically classified classifications (ICD10-CM major classifications) into 26 molecular classes. This server provides the MOA proteins, molecular functions, pathways for molecular classes, and individual diseases.
Notice: This server is freely available to all academic and non-commercial users.
Commercial users – to use this server, or request an evaluation copy, please send an email to Dr. Jeffrey Skolnick: skolnick@gatech.edu.
Citation: Zhou, H, Edelman B, Skolnick J. 2025. A mode-of-action protein based approach that characterizes the relationships among most major diseases. Scientific Reports: 15, 9668. https://doi.org/10.1038/s41598-025-93377-8 PDF
Please send questions to Dr. Hongyi Zhou: hzhou3@gatech.edu.