COVID-19 differentially expressed genes from37 ranked by their adjusted p-value that are mapped to the COSMIC36 database.
| Gene Name | Gene Description | padj | log2FoldChange | Up/down-regulated |
|---|---|---|---|---|
| NBN | nibrin | 2.0E-9 | 4.26 | Up-regulated |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 2.0E-9 | 3.72 | Up-regulated |
| WAS | Wiskott-Aldrich syndrome | 1.0E-8 | 4.63 | Up-regulated |
| RHOH | ras homolog family member H | 4.0E-7 | 4.72 | Up-regulated |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 4.0E-6 | 4.01 | Up-regulated |
| JUN | jun oncogene | 2.0E-5 | -3.57 | Down-regulated |
| BCL3 | B-cell CLL/lymphoma 3 | 6.0E-5 | 2.85 | Up-regulated |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) | 0.0002 | -4.36 | Down-regulated |
| PER1 | period homolog 1 (Drosophila) | 0.0004 | -4.34 | Down-regulated |
| RALGDS | ral guanine nucleotide dissociation stimulator | 0.0007 | -3.8 | Down-regulated |
| XPC | xeroderma pigmentosum, complementation group C | 0.001 | -3.98 | Down-regulated |
| GATA2 | GATA binding protein 2 | 0.002 | -3.95 | Down-regulated |
| NDRG1 | N-myc downstream regulated 1 | 0.002 | -2.72 | Down-regulated |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.002 | -3.83 | Down-regulated |
| CTCF | CCCTC-binding factor | 0.003 | -3.8 | Down-regulated |
| BCOR | BCL6 corepressor | 0.003 | -3.82 | Down-regulated |
| TET2 | tet oncogene family member 2 | 0.003 | 2.27 | Up-regulated |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.003 | 2.34 | Up-regulated |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.003 | -2 | Down-regulated |
| BCR | breakpoint cluster region | 0.004 | -3.66 | Down-regulated |
| TGFBR2 | transforming growth factor beta receptor II | 0.004 | -2.52 | Down-regulated |
| LZTR1 | leucine-zipper-like transcription regulator 1 | 0.005 | -3.66 | Down-regulated |
| JAK3 | Janus kinase 3 | 0.005 | 2.41 | Up-regulated |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.005 | -3.6 | Down-regulated |
| MLH1 | E.coli MutL homolog gene | 0.006 | -3.56 | Down-regulated |
| ZMYM2 | zinc finger protein 198 | 0.006 | -3.21 | Down-regulated |
| NAB2 | NGFI-A binding protein 2 | 0.006 | -3.55 | Down-regulated |
| CANT1 | calcium activated nucleotidase 1 | 0.008 | -3.14 | Down-regulated |
| TSC1 | tuberous sclerosis 1 gene | 0.008 | -3.21 | Down-regulated |
| NF2 | neurofibromatosis type 2 gene | 0.009 | -3.16 | Down-regulated |
| PML | promyelocytic leukemia | 0.01 | 1.86 | Up-regulated |
| ACVR1 | activin A receptor, type I | 0.02 | -3.18 | Down-regulated |
| VHL | von Hippel-Lindau syndrome gene | 0.02 | 2.11 | Up-regulated |
| LMNA | lamin A/C | 0.02 | -2.48 | Down-regulated |
| POU2AF1 | POU domain, class 2, associating factor 1 (OBF1) | 0.02 | 2.75 | Up-regulated |
| DDB2 | damage-specific DNA binding protein 2 | 0.02 | -3.16 | Down-regulated |
| RBM10 | RNA binding motif protein 10 | 0.02 | -2.34 | Down-regulated |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.02 | -2.04 | Down-regulated |
| TMPRSS2 | transmembrane protease, serine 2 | 0.02 | -2.89 | Down-regulated |
| HLA-A | major histocompatibility complex, class I, A | 0.02 | 2 | Up-regulated |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.02 | -2.22 | Down-regulated |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (14-3-3 epsilon) | 0.02 | 1.66 | Up-regulated |
| ARHGEF10L | Rho guanine nucleotide exchange factor 10 like | 0.02 | -3.05 | Down-regulated |
| PWWP2A | PWWP domain containing 2A | 0.02 | -3.05 | Down-regulated |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.02 | -2.21 | Up-regulated |
| EZR | ezrin | 0.02 | -1.95 | Down-regulated |
| APC | adenomatous polyposis of the colon gene | 0.03 | -3.01 | Down-regulated |
| EED | embryonic ectoderm development | 0.03 | -3.01 | Down-regulated |
| PLCG1 | phospholipase C, gamma 1 | 0.03 | -2.6 | Down-regulated |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.03 | -2.4 | Down-regulated |
| SFRP4 | secreted frizzled related protein 4 | 0.03 | -2.93 | Down-regulated |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.03 | 1.96 | Up-regulated |
| FES | FES proto-oncogene, tyrosine kinase | 0.03 | -2.9 | Down-regulated |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.03 | -2.35 | Down-regulated |
| ID3 | inhibitor of DNA binding 3, HLH protein | 0.03 | -2.34 | Down-regulated |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.03 | -2.78 | Down-regulated |
| CDK4 | cyclin-dependent kinase 4 | 0.03 | 1.67 | Up-regulated |
| CALR | calreticulin | 0.04 | 1.54 | Up-regulated |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | 0.04 | -2.86 | Down-regulated |
| TRRAP | transformation/transcription domain-associated protein | 0.04 | -2.39 | Down-regulated |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 0.04 | -2.84 | Down-regulated |
| LMO2 | LIM domain only 2 (rhombotin-like 1) (RBTN2) | 0.04 | 2.14 | Up-regulated |
| EPAS1 | endothelial PAS domain protein 1 | 0.04 | -2.24 | Down-regulated |
| AXIN2 | axin 2 | 0.04 | -2.82 | Down-regulated |
| AFF4 | AF4/FMR2 family, member 4 | 0.04 | -2.06 | Down-regulated |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 | 0.04 | -2.8 | Down-regulated |
| ASXL1 | additional sex combs like 1 | 0.04 | -2.08 | Down-regulated |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.04 | -2.33 | Down-regulated |
| SEPT9 | septin 9 | 0.04 | -2.21 | Down-regulated |
| PDE4DIP | phosphodiesterase 4D interacting protein (myomegalin) | 0.04 | -2.5 | Down-regulated |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.04 | -2.61 | Down-regulated |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.04 | -2.44 | Down-regulated |
| TPM4 | tropomyosin 4 | 0.05 | 1.6 | Up-regulated |
| BRD3 | bromodomain containing 3 | 0.05 | -2.74 | Down-regulated |
| SEPT6 | septin 6 | 0.05 | 1.62 | Up-regulated |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.05 | -2.55 | Down-regulated |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (AF10) | 0.05 | -2.41 | Down-regulated |
| RPL10 | ribosomal protein L10 | 0.05 | -1.56 | Down-regulated |
| FGFR1 | fibroblast growth factor receptor 1 | 0.05 | -2.36 | Down-regulated |
| NOTCH2 | Notch homolog 2 | 0.05 | -2.49 | Down-regulated |
| MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.05 | -2.33 | Down-regulated |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.05 | -1.75 | Down-regulated |