Center for the Study of Systems Biology

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Valsci

How information flows through Valsci’s modular data processing structure.

The rapid expansion of scientific literature presents significant challenges in efficiently verifying claims and synthesizing evidence. Valsci addresses this issue by providing an open-source, self-hostable utility that automates scientific claim verification through retrieval-augmented generation (RAG). By integrating actual excerpts from academic literature and bibliometric scoring (H-index, citation counts, journal impact), Valsci significantly reduces citation errors and improves verification accuracy.

Valsci efficiently handles hundreds of claims per hour, making it ideal for large-scale systematic reviews, meta-analyses, and hypothesis validation in bioinformatics, computational biology, and related disciplines.

Details described in the following publication:
Edelman, B, Skolnick J. In Press. Valsci: An Open-Source, Self-Hostable Literature Review Utility for Automated Large-Batch Scientific Claim Verification Using Large Language Models. BMC Bioinformatics: 26: 140. https://doi.org/10.1186/s12859-025-06159-4. PDF

Source Code
The source code of Valsci is freely available on GitHub under the GNU General Public License (GPL) v3.

Data Set
Valsci uses datasets accessible via the Semantic Scholar Open Research Corpus (S2ORC) and the Semantic Scholar API. Setup scripts and detailed instructions for data access are provided on the project’s GitHub repository.

Questions and Comments
Please direct questions and comments to: Brice Edelman and Jeffrey Skolnick.

  • Skolnick Research Group
    • Jeffrey Skolnick
    • Maximilian Brogi
    • Brendon Cara
    • Chad Choudhry
    • Brice Edelman
    • Jonathan Feldman
    • Jessica Gilmore Forness
    • Bartosz Ilkowski
    • Preetam Jukalkar
    • Giselle McPhilliamy
    • Asha Mira Rao
    • Hargobind Singh
    • Kyle Xu
    • Hongyi Zhou
    • Former Group Members
  • Software and Services
    • Services
      • DESTINI
      • DR. PRODIS
      • ENTPRISE
      • ENTPRISE-X
      • FINDSITEcomb
      • FINDSITEcomb2.0
      • FRAGSITE
      • FRAGSITE2
      • FRAGSITEcombM
      • Know-GENE
      • LeMeDISCO
      • MEDICASCY
      • MOATAI-VIR
      • PHEVIR
      • PICMOA
    • Downloads
      • AF2Complex
      • AF3Complex
      • APoc
      • Cavitator
      • DBD-Hunter
      • DBD-Threader
      • EFICAz2.5
      • Fr-TM-align
      • GOAP
      • iAlign
      • IS-score
      • LIGSIFT
      • MENDELSEEK
      • PULCHRA
      • SAdLSA
      • Valsci
    • Databases
      • Apo and Holo Pairs
      • New Human GPCR Modeling and Virtual Screening
      • PDB-like Structures
    • Simulations
      • E. coli Intracellular Dynamics

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