This pre-print work lead by Dmitry Leontyev entitled “Ultrahigh Resolution Mass Spectrometry Imaging Maps Brain Lipidome Alterations Associated with Mild Traumatic Brain Injury” published in bioRxiv demonstrates the use of next generation ion mobility instrumentation to gain more insight on mTBI pathology, a non-targeted spatial metabolomics workflow utilizing ultrahigh resolution mass spectrometry imaging was developed to measure brain region-specific lipid alterations in rats.
Archives for January 2024
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This work lead by Xin Ma entitled “Triboelectric nanogenerator-coated blade spray mass spectrometry for volume-limited drug analysis” published in the International Journal of Mass Spectrometry shows it is possible to extract and analyze drug samples in a pulsed fashion at sub-nanogram to picogram levels with good stability and reproducibility using coated scalpel blades.
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This collaborative work entitled “Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors” published in diabetes investigated the link between enhancement of SI (by hyperinsulinemic–euglycemic clamp) and muscle metabolites after 12 weeks of aerobic (high-intensity interval training [HIIT]), resistance training (RT), or combined training (CT) exercise in 52 lean healthy individuals.