We are excited to share that our recent work, led by current student Eric Gier and recent graduate Dr. Dmitry Leontyev, entitled “Multipass CCS Refiner: A Web Application for Accurate Collision Cross Section Calibration in Cyclic Ion Mobility-Mass Spectrometry”, has been published in the Journal of the American Society for Mass Spectrometry.
The Multipass CCS Refiner is an open-source, Shiny-based application that automates CCS refinement in cyclic ion mobility instruments using the Lin & Costello perturbation-correction approach. By making this resource freely available, we aim to support the mass spectrometry community in adopting multipass CCS calibration and to accelerate research relying on high-confidence CCS measurements.