The Integrative and Quantitative Biosciences Accelerated Training Environment at the Georgia Institute of Technology (InQuBATE @ GT) National Institute of General Medical Sciences (NIGMS) T32 training grant was established in July 2021. The InQuBATE training program will train a new generation of scientists to understand the dynamics, structure, and function of integrative, living systems given uncertainty. The program will leverage curricular developments in biological theory and modeling as well as data analytics and machine learning to help trainees develop a mechanistic understanding of integrative living systems spanning molecules, cells, to populations. InQuBATE will embrace a training approach that emphasizes discovery-driven approaches in biology by fostering a training environment that inculcates a quantitative mindset, and not just a quantitative toolset. Our long-term goal is to develop a scalable training model to meet the needs of 21st-century challenges through immersive integration of quantitative and data science methods into all aspects of the life science training pipeline. The training program will support cohorts of three PhD students per year, each supported for two years, and mentored by InQuBATE faculty trainers.