Instructional Laboratories – Biomedical Engineering

Whitaker Building, Wallace H. Coulter Department of Biomedical Engineering on Georgia Tech Campus
Instructional Laboratories at GT BME
"We challenge our students to own their laboratory experiences and engineer strategies to interfere with the physiological processes that lead to cancer. Student teams develop their own comprehensive research proposals, which then become the foundation for experimental validation in the lab and employing relevant techniques.”
Induction of Apoptosis (programmed cell death) in glioblastoma (brain cancer cells) using an inhibitor of cancer-specific activated pathway

About:

Instructional Laboratories of the Wallace H. Coulter Department of Biomedical Engineering of Georgia Institute of Technology and Emory University is located in the Whitaker Building at the Georgia Tech campus. Several research courses are supported by the Instructional Laboratories including Quantitative Engineering Physiology I & II, Cellular and Tissue Engineering courses. Resources and support are provided for other graduate and undergraduate courses (for details, see courses section). The Laboratories, in addition to several biosafety cabinets and CO₂ incubators, also house state of the art instrumentation including Flow cytometers, QuantStudio Real Time PCR system, QIAcube, Nanodrop, fluorescent and phase contrast microscopes with live cell imaging capabilities, IR imager for Western analysis, plate readers, hypoxia incubator, electrospinning equipment and set up for nanoparticle and microparticle fabrication. Undergraduate as well as graduate students use the instrumentation and resources for their research. A major focus of the research is student-initiated research projects involving engineered strategies to tackle real world medical problems by performing hands-on experimentation that generate solutions and create value for the biomedical field.

News/Events:

2024 publication in Nature Scientific Journal – Multifaceted impact of HIV inhibitor dapivirine on triple negative breast cancer cells reveals potential entities as targets for novel therapy.

2023 publications: 1) Disruption of Glioblastoma Multiforme Cell Circuits with Cinnamaldehyde Highlights Potential Targets with Implications for Novel Therapeutic Strategies and 2) Multifaceted Effects of Kinase Inhibitors on Pancreatic Cancer Cells Reveals Pivotal Entities with Therapeutic Implications.

2022 publications: 1) Casticin Impacts Key Signaling Pathways in Colorectal Cancer Cells Leading to Cell Death with Therapeutic Implications and 2) Disruption of Colorectal Cancer Network by Polyphyllins Reveals Pivotal Entities with Implications for Chemoimmunotherapy.