Center for the Study of Systems Biology

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    • Jeffrey Skolnick
    • Maximilian Brogi
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Preprints

Zhao, H, Velez C, Naravane A C, Saha A, Feldman J, Skolnick J, Murray D, Honig B. Combining structural modeling and deep learning to calculate the E. coli protein interactome and functional networks. bioRxiv 2025.05.07.652715; doi: https://doi.org/10.1101/2025.05.07.652715. PDF

Feldman, J, Skolnick J. 2025. AF3Complex Yields Improved Structural Predictions of Protein Complexes. bioRxiv 2025.02.27.640585; doi: https://doi.org/10.1101/2025.02.27.640585. PDF

Gao, M, Nakajima An D, Skolnick J. 2022. Deep learning-driven insights into super protein complexes for outer membrane protein biogenesis in bacteria. bioRxiv 2022.08.25.505253; doi: https://doi.org/10.1101/2022.08.25.505253. PDF

Gao, M, Nakajima An D, Parks J M, Skolnick J. 2021. Predicting direct physical interactions in multimeric proteins with deep learning. bioRxiv 2021.11.09.467949; doi: https://doi.org/10.1101/2021.11.09.467949. PDF

Astore, C, Zhou H, Skolnick J. 2021. LeMeDISCO: A computational method for large-scale prediction & molecular interpretation of disease comorbidity. medRxiv 2021.06.28.21259559; doi: https://doi.org/10.1101/2021.06.28.21259559 PDF

Gao, M, Skolnick, J. 2021. A general framework to learn tertiary structure for protein sequence annotation. bioRxiv 2021.04.01.438098; doi: https://doi.org/10.1101/2021.04.01.438098. PDF

Astore, C, Zhou H, Jacob J, Skolnick J. 2021. MOATAI-VIR – an AI algorithm that predicts severe adverse events and molecular features for COVID-19’s complications. medRxiv 2021.01.29.21250712; doi: https://doi.org/10.1101/2021.01.29.21250712. PDF

Yamashita, D, Botta D, Cho HJ, Guo X, Ozaki S, Flanary V L, Sirota I, Gao M, Yamaguchi S, Nakano M A, Zhou F, Zhou H, Kondo T, Kunieda T, Crossman D K, Kornblum H I, Gorospe M, Nam D, Zamboni N, Skolnick J, Gu Z, Lund F E, Nakano I. 2020. Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge. bioRxiv 2020.11.26.399725; doi: https://doi.org/10.1101/2020.11.26.399725. PDF

Publications

  • Skolnick Research Group
    • Jeffrey Skolnick
    • Maximilian Brogi
    • Brendon Cara
    • Chad Choudhry
    • Brice Edelman
    • Jonathan Feldman
    • Jessica Gilmore Forness
    • Bartosz Ilkowski
    • Preetam Jukalkar
    • Giselle McPhilliamy
    • Asha Mira Rao
    • Hargobind Singh
    • Kyle Xu
    • Hongyi Zhou
    • Former Group Members
  • Software and Services
    • Services
      • DESTINI
      • DR. PRODIS
      • ENTPRISE
      • ENTPRISE-X
      • FINDSITEcomb
      • FINDSITEcomb2.0
      • FRAGSITE
      • FRAGSITE2
      • FRAGSITEcombM
      • Know-GENE
      • LeMeDISCO
      • MEDICASCY
      • MOATAI-VIR
      • PHEVIR
      • PICMOA
    • Downloads
      • AF2Complex
      • AF3Complex
      • APoc
      • Cavitator
      • DBD-Hunter
      • DBD-Threader
      • EFICAz2.5
      • Fr-TM-align
      • GOAP
      • iAlign
      • IS-score
      • LIGSIFT
      • MENDELSEEK
      • PULCHRA
      • SAdLSA
      • Valsci
    • Databases
      • Apo and Holo Pairs
      • New Human GPCR Modeling and Virtual Screening
      • PDB-like Structures
    • Simulations
      • E. coli Intracellular Dynamics

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